Baszucki Family Vascular Surgery Biobank: A Resource for Translational Vascular Research

Introduction: The Baszucki Family Vascular Surgery Biobank, established in fall of 2022, is a biorepository of vascular samples (blood and tissue) within the division of Vascular Surgery supported by the Baszucki Family. It is a brilliant resource for the vascular community to study and better understand the causes of spectra of vascular diseases like peripheral artery disease, carotid artery disease and aneurysms, for discovering new drugs and therapeutics for vascular diseases management.  

Methods: The vascular patients who would undergo surgery are consented in the clinics for the sample collection. Blood and vascular tissues are procured during the time of the surgery. Blood is processed to isolate plasma and PBMCs and tissue is snap frozen/OCT embed, and then preserved in cold storage (-80 degree and LN2) for future scientific studies. Genomics and patient-specific iPSC studies are used to understand the mechanisms of vascular disease and develop new therapeutic for biomedical care of the patients.

Results: Since 2022, we have consented and collected samples from more than 430 vascular patients across the spectrum. This would help in providing new insight into the genetic components and mechanisms of the vascular diseases.

Conclusion: Our Biobank’s mission is to serve the research community for accelerated biomedical vascular research through the integration of excellence and innovation in science to develop therapeutic strategies for translational research and in designing a more personalized treatment plan for vascular patients.